Recent Advances in Brain Targeted Drug Delivery Systems: a Review
نویسندگان
چکیده
Drug delivery to the Central Nervous System (CNS) in treatment of CNS related disorders is very complicated and challenging. Although some neuropharmaceutical agents have great potential for treating CNS disorders, major challenge to CNS drug delivery is the Blood Brain Barrier (BBB), which limits the access of drugs to the brain. Progress in brain drug delivery has lagged behind other areas because of the restrictions posed by the BBB. This review encompasses detailed discussion of some of the recent drug delivery systems like Dendrimers, Polyanhydrides, Lipoplexes, Polyplexes, Scaffolds, Convection-enhanced delivery, and Modified nanoparticles for targeting drugs to the brain.
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